Muhammed F. Aljerari and H. John Sharifi, PhD

The Elusive Lessons of Encephalitis Lethargica

Tags: autoimmune diseases clinical COVID-19 disease infection neurologist

Encephalitis Lethargica (EL) emerged as a deadly pandemic in the early 20th century, leaving many permanently disabled. Though rare today, its cause remains unknown. EL has two forms—dyskinetic (children) and Parkinsonian (adults). Researchers suspect links to influenza and COVID-19 due to shared neurological effects. Treatment is limited, and future viral pandemics could trigger EL’s return.